That's kind of like asking whether putting miles on rubber tires will eventually wear them out.

Some wear longer than others.
I don't keep all the dates and revisions in my head (who could, with S&W's virtually constant revisions?

), but if I remember right, the Endurance Package changes were introduced in the stainless models with the introduction of the 629-4 Classic (I have one). I also have an early production Redhawk .44MAG, BTW.
Back before I went to a S&W revolver armorer class, I relied upon the head armorer at my agency to maintain my S&W revolvers (he did S&W and Colt, and looked down his nose at Rugers

). He had to replace the original hammer & trigger in my 629-4, which I'd bought LNIB from another cop (who wasn't a Magnum revolver enthusiast), because of a SA push-off problem that couldn't be adjusted because of the tolerances present in the factory parts. (The "Golden Days" of S&W

)
Once that problem was corrected, and having had the 629 MagNaPorted & bead-blasted at some point (mea culpa for my younger age and interest in "cosmetic surgery" back then), I put a fair number of both factory and some heavy handloads through it. The second time the armorer had to adjust the carry-up (timing, if you'd prefer), he suggested I consider saving the heavy handloads for the Ruger and stick to factory Magnum loads through on the 629-4. I only run the occasional stout 315gr loads through the 629 anymore.
I'm no longer an avid reloader, either, so I don't expect to wear out the 629.