I'd say it depends on your deck height relative to the slide? If the stock irons are adequate for a 30% (?) sight picture, I'd stick with that. Otherwise, mount your dot, and get your caliper out to determine how much additional sight height you need to clear for your preferred sight picture. Then use that number to go pick a set of sights. Dawson makes custom ones, but you can find other makers as well these days.
Shooting competition, I never changed the factory sights on my Glock 34. I ran it wit a 507c on a FCD plate. This was USPSA though, so YMMV.
Personally I look at the target, not the optic/sights. I guess you could say I look "through" the sights, like you look through a car windshield. I'm aware of the dot/front sight, but I don't focus in on it.