Right now I have the 155 grain XTP as my carry load for my Glock 22. I like the velocity of the 155 grain and the XTP's penetration. A good combination for me. Lots of other good choices as well. I think you would have to work pretty hard to find a bad 155, 165, or 180 grain JHP. The 40 S&W loads have been pretty well perfected over the years.