Yeppir. I have one. I like it. A lot.
Last fall I had two of them, one with a Streamlight for HD. After awhile I began to think investing over $600 in a HD gun that simply sits around was not wise, so I sold the gun and light, but kept the other P365 for EDC. I've shot that gun in three IDPA matches, including a large sanctioned match last winter in Phoenix, two USPSA matches and two BUG matches. The gun has never even hiccuped.
I will admit, I had to adapt my magazine changes to using my left thumb to hit the mag release button on the way to my mag carrier and I have to be careful when I insert the new mag under match pressure. I've only done it once, but pinching a bit of flesh when you slam the mag home is a b***h and it's damn hard to get that finger free again without dropping the mag. It can be done, but I guarantee a blood blister for the trouble.
I've found with my sized hands that I can get part of my pinky on the gun with the flush 10-round mag and all of my pinky on it with the 10-rounder and extended base plate, so I've got three of those, one flush and three 15-rounders (for the USPSA and IDPA matches). For carry I use the flush in an AIWB rig or a kydex IWB at 3:30, depending on the day's activities. The 15-rounder is my backup mag.
On the other hand, nostalgia won out and I bought a used G26.4 from a fellow GT member and it feels like old home week in a Galco Ultimate Second Amendment AIWB horsehide holster. I'll switch off, depending on clothing and planned activities. The G26 has always performed well in my hands with my limited capabilities; in fact, I ran the IDPA's old Classifier match with a G26 and three 15-round mags with X-Grip adapter and I made Expert with the little gun. That endears it to me.
For HD I invested in a reasonably-priced G23.4 and an Olight Valkyrie tac light, simply because I've shot a G23 and CC'd one in the past and I like the .40 caliber option, especially during these times. It might get CC use again in cold weather when people are dressed in layers (including me). I've got an IWB kydex for 3:30 wear with the G23/with light.
Which brings me to my last gun in my little arsenal: my little LCPII. I can shoot the snot out of this gun or it would be long-gone. I think it will always have a place as a pocket alternative, even compared to the Sig, but where it really shines is in an ankle rig on long drives.
OP - One thing to note with the Sig: the grip texture is a bit tough on bare skin, so in warmer weather it can chafe a bit. I dealt with that by lightly sanding the left side of the grip until it's become noticeable but bearable.
The gun is quite remarkable. There is a reason it's won so many awards. I'm closing in on 2,000 rounds (roughly) and it's shot several types of ammo My CC ammo is Federal HST 124-grain standard pressure. I've shot several mags of this ammo in matches and the recoil isn't a problem at all; still can make fast double taps and head shots out to 20 yards.
For now, I'm keeping the G26 AND the Sig. Who knows what the future holds?