I have been carrying .45, everywhere, for a long time.
Lately I've been rethinking my carry options, and it's looking like this:
Around the farm, a G40 (10mm) or a 6" S&W 686 (.357 magnum), in a chest holster. My encounters tend here to be with four-legged critters, and prefer to maintain a good distance, when possible. The .45, I'm finding, doesn't have the best trajectory for anything over 10 yards.
When going to town, in the summer, when clothing is light, I'll switch to my 9mm Kahr P9. It's a single stack, but I shoot pretty well with it. Plus one extra mag.
In town, in all other seasons, I'm probably going to continue carrying .45, in a Walther PPQ, with one extra mag. We'll see.