Dunno... if I shoot it... of course! Actually, I was sitting bored in my gun club's board meeting earlier tonight and there was a gun magazine on the table. I thumbed through it and there was an article by Mas about carrying extra ammo for various situations - not just SD. In one instance in the article he related (as I remember) taking 6 shots (with one miss) to dispatch a large snake. These nonnative pythons can reach 17' long and have thick bodies. They aparently move slowly so I suppose one well-placed head shot would do it - or 6 or 8 shots with misses - kinda like GSSF plates.