It seems like the 45 acp and 10mm Glocks are the toughest ones to get a grip on. I think Glock uses the same slide lock on all of their guns, and with the larger calibers having wider frames, the lever just seems way too short. I've never had any trouble disassembling my 19 or my 26, but have put extended levers on my 21 and 30s just to be able to grip it enough to take the slide off.
I have remove my slides one handed with two fingers through the trigger guard as I pull the lock w/ my finger and thumb as I depress the slide by noseing it straight down on my workbench.
I finally did it once on my G36 after several many attempts and then got an extended lock from the Glockstore.
They had to hunt for one as they are unique.
I was there getting a ZEV trigger kit installed, also unique,
so they slipped me an extended lock and an extended slide lock lever, also unique, for free.
Recently I went there and got one of their milled extended slide lock for my new G41.
It is just enough longer to make the difference.
It's also slightly thicker and sturdier.
Their pitch for it is that it is more consistent and will improve accuracy.
Maybe so ... I'm too shakey of a one hand shot to tell.
Still, it is a fine little piece part and worthy of consideration.
http://www.glockstore.com/custom-parts-amp-accessories/precision-slide-lock-1
Batts