I have an LCR 38, SN of 540-32xxx. Yesterday I shot 40 Winchester 130 grn, FMJ and 30 Speer Gold Dot 53921, 38 + P, 135grn. Towards the end of the session, I fired from retention, unsupported, using the Speer +P. Right handed, no issue. Left handed, the cylinder opened every round or two, thru 15 rounds. I loaded 5 of the Winchester FMJ and the cylinder remained locked, when fired left hand, unsupported, from retention. When searching the interweb, for similar issues, I wondered if maybe my hand somehow bumped the crane latch. I can't imagine how. I have small hands.