I was a .45 guy for lots of years. 20 of them in the US Navy. I carried a Colt 1911, as well as a Springfield. Also a Taurus. You could not talk me into a .40 back then, as it was a comparatively "new round". Now that I'm older, (and wiser) I find the .45 a little heavy to carry, and shoot. Do the ballistics on the .40.......I now run a SIG SP2022 in .40. I load Hornady Critical Defense 135 Grain JHP, for SD. I practice with Whitebox 180 Grain FMJ. Nothing wrong with a .45, but, as I said, I have old hands, and a bit of arthritis, So I find the .40 easier to shoot. 12+1 has an advantage over 7+1....I'll (God willing) probably never NEED 13 rounds, but it's good to know I have that capability, should the situation call for it.