As I get older I am at the very early stages of joint pain. When not working I go and walk or ride bicycle or skate about 1 hour a day at a pace that raises HR to the 60-70% of max level. I have begun using low levels of NSAIDS. I know they can be damaging to the liver if used regularly and then over time their effectiveness wains and then higher levels are required to work, further risking lever damage. I'm going to give it a 3 month trial. I'll go pick out a brand version of a vitamin I already use and give it a 3 month shot. I'll get back to you with some results, I'm about to get busy outdoors and this will give me a better indication if my condition worsens with additional use or it seems that the glucosamine seems to help.