At close range the difference is insignificient. If you see significient changes on the handgun target range its most likely secondary to firing method.:wavey:
I must respectfully disagree. It is not uncommon to see a 2" difference in POI on targets as close as 7yds when comparing 115gr vs 147gr bullets.
If all you are trying to do is shoot a full-sized target anywhere on the cardboard at 7 to 10 yds, this difference may be negligible but, if you are trying to accomplish a challenging shot such as an upper "A" zone hit on a USPSA at 35 yards, you better know your pistol's POI in reference to your POA. A variation of several inches on a 35 yd target is HUGE and, when making tight shots, said difference may cost you valuable points.
I do want to reiterate what I mentioned before: the bullet weight is not the only variable that affect the bullet's trajectory. We must also consider all the other variables of the reloading components (powder, powder charge, OAL, etc). Granted that the shooter's input will have a measurable effect due to their handling technique. Nonetheless, bullet weight alone, will affect how the bullet prints on paper.