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Don't fool yourself....no 12gauge slug will ever equal an elephant rifle.
Personally i would definitely trust a 12 gauge brenneke or dixie slug on a charging bear. But 600grs at 1500fps is not the same as a .500 NE or a .458 Lott. 3000ft lbs vs 5000+ft lbs.

The real comparison would be 12 gauge vs .45-70 for bear protection
the handling capabilities would be close
the second shot capability would be close
and the power is close
 
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