I have a question regarding the .45 Colt and whether or not it is adequate for whitetail deer. I know a .44 magnum would be the better choice, but I don't have one, nor will I have the funds for one in the foreseeable future. I have a S&W Model 25 with a 5 inch barrel I can shoot cloverleaf with at 20 paces. That would be a long shot where I plan on hunting, because it is a swampy area. I am trying to decide between loading a hardcast lead, 250 grain semi-wadcutter, going at around 900fps, or using Winchester Silvertips. I would have no hesitation using it against a 200lb. man, so I figure either load would do well on a 100-150 lb. deer. I should add that my hunting is going to be very limited this year due to health issues. I am taking 2 different blood thinners for a clot in my leg, and will be using my atv to get to and from where I will be hunting. I normally would use a rifle, but I bruise so damn easily because of the blood thinners I really don't want to shoot a rifle right now. Any advice will be greatly appreciated.