I never would have considered trying it. The question was posed in one of those "ask the expert" pages of a magazine I read recently, Shooting Times I think, can't find it now. The guy asking the question claimed to have run some test loads with success, saying the velocities were a bit faster than the same load with a small pistol primer, but no other obvious problems. Anyone here ever heard of this? Wanna kill these ads? We can help!