The only handgun I see in my hand with .22 Rimfire in it, the S&W 63, the curse of .22 LR, it can misfire, with the Revolver, press the trigger again! I remember well the test from a .22LR scoped rifle, 250 yds, right through a Turkey, and the frozen bag of guts in side of it! Translate that to 5 yds, and 3 in the sternum! The only reason to point a gun at an attacker? To kill them! That is the only reason you can shoot some one, they are going to kill you! Or some other innocent person. You believe this is so, as a reasonable person, you shoot them, a lot! Many years ago I was stabbed on two separate occasions, in defending myself, and prevailed, (just with hands and feet) now I carry, but do not even frequent the type of Clubs I worked in then. If you are real close, the face is your bulls eye.