For self defense I usually use Golden Saber 185 grain JHP. I picked up Federal Premium .45 165 grain hydra-Shok JHP. In regards to the grain is the 165 grain to little? Or should I be up around 185 grain. Im not an expert on ammo grains. What grain should I be using in self defense? Thanks for advice ahead of time. Wanna kill these ads? We can help!