http://www.suntimes.com/news/24-7/2645214,villarreal-guilty-road-rage-murder-082710.article http://www.suntimes.com/news/24-7/2642896,CST-NWS-finger27.article Road rage incident leads to shooting back in 1981. Killer finally found and brought to justice. Killer used a 22 and hit the victim twice killing him. Interesting article from the caliber angle. I would never carry a 22 for self defense - but it does go to show you how important shot placement is, regardless of the caliber you carry.