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::FDA:: Don't take your drugs with grapefruit juice!

Discussion in 'The Okie Corral' started by lethal tupperwa, Nov 27, 2012.

  1. lethal tupperwa

    lethal tupperwa

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    ::FDA::

    Don't take your drugs with grapefruit juice!

    That's not a bad rule to follow, because enough drugs have been prove to have some very harmful side effects if you do.

    Side effects from taking them with grapefruit juice can be as severe as death.

    85 oral medications, including pills for heart problems, pain and psychiatric problems have been put on the "no Grapefruit juice" list:

    A-C
    Alfentanil (oral)
    Amiodarone
    Apixaban
    Atorvastatin
    Buspirone
    Clopidogrel
    Crizotinib
    Cyclosporine

    D-F
    Darifenacin
    Dasatinib
    Dextromethorphan
    Domperidone
    Dronedarone
    Eplerenone
    Erlotinib
    Erythromycin
    Everolimus
    Felodipine
    Fentanyl (oral)
    Fesoterodine

    H-P
    Halofantrine
    Ketamine (oral)
    Latatinib
    Lovastatin
    Lurasidone
    Maraviroc
    Nifedipine
    Nilotinib
    Oxycodone

    P-Z

    Pazopanib
    Pimozide
    Primaquine
    Quinine
    Quetiapine
    Quinidine
    Rilpivirine
    Rivaroxaban
    Silodosin
    Simvastatin
    Sirolimus
    Solifenacin
    Sunitinib
    Tacrolimus
    Tamsulosin
    Ticagrelor
    Triazolam
    Vandetanib
    Venurafenib

    Verapamil
    Ziprasidone
     
  2. Atomic Punk

    Atomic Punk

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    besides grapefruit being disgusting anyway. what on earth in it makes it have such negative effects with so many drugs?
     

  3. robertoh

    robertoh

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    Seen a episode of the Dr. Oz show last week and he was talking about diets for loosing weight,and said Grapefruit juice was good for a weight reduction.He didn't mention any caution about not drinking Grapefruit just if taking some Medications. So much for the all wise Dr. Oz.:whistling:
     
  4. Travclem

    Travclem Badass Member Lifetime Member

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    It is a potent inhibitor of Cytochrome P450 enzyme 3A4 that plays a big role in the hepatic metabolism of a lot of drugs. If you drink grapefruit juice your body cant get rid of the drug thus it accumulates to toxic levels.
     
  5. deputy tom

    deputy tom

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    ^^ Yep! I knew this as it's written on my meds label. Thanks for posting for those who didn't know. tom.
     
  6. Atomic Punk

    Atomic Punk

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    that is really interesting. may or may not mention that to people i know that eat grapefruit :supergrin:
     
  7. DustyJacket

    DustyJacket Directiv 10-289

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    And grapefruit itself.
    Back in the early 1990s, my parents sent us a case of Ruby Red grapefruit, and we ate a lot of it.

    My wife semi-ODed on her normal meds. We researched it and went back to her doctor with the news. He didn't know. few people really did.

    A couple of weeks ago, she forgot and bought some GF juice. She started feeling dizzy the next day.........
     
  8. SMOKEin

    SMOKEin

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    Am I the only one who always thought you were supposed to take your drugs with whiskey?
     
  9. jtmac

    jtmac Señor Member

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    The mystery of how and why people drink grapefruit juice to begin with remains...
     
  10. fwm

    fwm

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    Add Warfarin to the list. Probably a number of GTers on it. Alters how it works and makes the INR tests mostly useless, culminating in prescribed doses being way to high or to low. Results can be devastating, as my wife found out after the hospital called me a 6:00 in the morning to get there NOW if I wanted to see her again.
     
  11. deputy tom

    deputy tom

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    No, you aren't but it's Whisky. tom.:tongueout:
     
  12. Dennis in MA

    Dennis in MA Get off my lawn

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    We took druuuuugs and grapefruit juice. Look what happened to us!

    [​IMG]



    (OK, maybe we just came from the eye doctors. LOL)
     
  13. alwaysshootin

    alwaysshootin

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    Actually, when taking drugs, it's vodka, that should be used!

    Whiskey, is actually, medicine, on it's own! :whistling:
     
  14. Travclem

    Travclem Badass Member Lifetime Member

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    Yes, Warfarin is definitely on the list.