Well, my wife done clicked the wrong popup again. This time none of the anti-malware programs will run, and it has my "System Restore" disabled. Any time I try to run any of the programs, "Malwarebytes", "Superantispyware", "HiJackThis", or "ComboFix", none will run except for "HiJackThis", and it comes back showing that everything is fine. I even deleted McAfee (again), because it was running in safe mode. This crap did something to my registry to where I can't even run any of these programs in safe mode. I'm about to reformat and reinstall Windows (again). Sigh. I told my wife that this is the last time, and that next time she can learn this stuff for herself. I download these programs on my laptop, then transfer them via memory stick to the desktop PC, and they won't run on it. She's pretty sure she clicked "OK" on a popup that asked if she wanted to fix her spyware problem.