This stuff is all an exercise in balancing the various parts of the overall "compromise" you're willing to accept. These things may look like a huge Venn diagram, with different parts being: *Feeding reliability *Extraction/ejection consistency (slide run & recoil force) *Inherent & practical accuracy in any particular gun *Controllability & recoil management *Bullet design *Velocity window for optimal expansion Where do these things overlap in your gun, being handled & fired in your hands, using your selected ammunition, on whatever day you check, in whatever range of weather/environmental conditions exist at that moment in time? Dunno. Can't predict such things. All I know is that I tend to prefer using standard pressure loads, myself, offered by one or another of the major American ammo makers, using a modern hollowpoint of 230gr weight. The rest is up to me. Sure, I've used +P (as both approved/purchased & issued loads), and I still have a supply of it in a couple of brands/bullet weights, but I prefer to keep it aside for my larger .45's, for the most part. I've also used 185gr & 200gr loads, going back for years. As long as they feed & optimally function in my .45's, in my hands, when the guns are being run fast & hard (under demanding conditions of different courses-of-fire), I'll not lose any sleep if I have to use them. I just prefer the 230gr loads, given my druthers. My preference for 230gr loads was one of the reasons I didn't add any .45GAP guns to my working collection. (That, and the fact that my hands fit the standard size .45 ACP guns just fine.) Winchester managed to put a 230gr bullet into their GAP offerings, but it wasn't easy to find at any of the stores within a couple of the counties where I live & worked. I don't care to use a cartridge which can't be easily found among gun & sporting goods stores. Call me old-fashioned, if you will. I liked the idea of a subcompact .45 similar in overall size to my G26's/27 ... but I already enough compact/subcompact .45's, and I'm decently invested in small .40's, too. The shooter-variable in using .45 +P needs to be considered, too. I can't remember if I already mentioned it in this thread topic, but I still remember being called to assist a small agency with their familiarization and qualification using their brand new G30's several years ago. Their ammunition of choice? A well known brand of 200gr +P hollowpoint. More than half a dozen of their shooters had repeated feeding & functioning issues with the guns that day, all of whom were expressing some level of dissatisfaction with the felt recoil of the 200gr +P load chosen. One of them was even an existing G30 owner (and someone who claimed to be a gun enthusiast). He said he didn't use +P loads in his own G30, and it appeared he wasn't particularly comfortable with the felt recoil of his new issued G30 using the +P loads. Bottom line? I learned a few months later that their agency had traded their G30's for G23's, and had selected one of the good quality LE-only 180gr loads. I was told they were very pleased with the change. I always wondered if their experience might have been different if they'd been willing to use standard pressure 230gr loads in their G30's, though. My prioritization of earlier still remains. More range training/practice time ... less over-analyzing of subtle (real or perceived) nuances of specific ammunition choices. Good familiarity with the weapon, meaning safe and proper manipulation, as well as maintenance (which can be where some folks seem to get really derailed in their practices ). Good holster selection and carry method if the gun is lawfully carried as a dedicated defensive weapon. Applicable to anticipated needs and circumstances. Good user understanding and practiced skillset using that carry method & holster selection. Good quality ammunition ... which in my case means preferably made by one of the major American ammo makers who have acquired a lot of experience in making ammo which meets the Q& performance specifications of LE/Gov users. (Obviously, the ammo selection needs to be legal to possess and use within whatever local laws may exist.) Then remember, when using smallish .45's it isn't unknown for them to be less tolerant of both shooter & ammunition influences. Choose wisely. Training & practice. (The needs of different people in this regard can be ... different.) Mindset. Over the years I've increasingly become prone to respond to questions of gun make/model, caliber and specific ammo choices by taking the person asking me such questions ... (especially those wanting to hotly debate or even argue with me about it) ... downrange to the firing line. I have them run through some demanding drills and/or courses-of-fire, which are unexpected and done cold (they don't get to watch others do them first), and which might stress them a bit. Then we discuss how things went. I do this to myself, or have other instructors do it to me, just to try and keep things in perspective. Worry about first things first, in the real world ... unless it's the internet, of course.