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Personally, I suggest a more powerful handgun.
There's nothing in .380 that I personally trust. But, if you're locked in to the .380 concept, you might want to try Hornady Critical Defense. I've heard that LAPD adopted this load for optional backup/off duty guns in this caliber. Should have some feedback from the field before long. LAPD is sharp and they wouldn't have adopted it without being satisfied with testing results.
best,
Mas
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