Personally, I suggest a more powerful handgun.
There's nothing in .380 that I personally trust. But, if you're locked in to the .380 concept, you might want to try Hornady Critical Defense. I've heard that LAPD adopted this load for optional backup/off duty guns in this caliber. Should have some feedback from the field before long. LAPD is sharp and they wouldn't have adopted it without being satisfied with testing results.