When I carry my G22, I have 180 HST in the gun, and Double Tap's 180 Gold Dot in the spare mag.
I do this mainly to have different choices, or if I happen on a situation where I think I might need the extra penetration of the bonded GD I can switch if I have time. I would trust either to tear a car apart on the way through.
17.4 (6), 19.3 (2), 19.4, 20.4, 21.4 (2), 26.4, 27.4
The 10mm has so much stopping power, it can even put an end to the caliber war.