That is quite a lot. Like WiskyT, I use Unique all the time & it meters to 1/10gr. I did polish the interior of my Dillon & itis the newer measure w/ the safety return bar. It pretty much makes the measure run the same each stoke. Are you using the small pistol bar? The larger rifle bar is too big.
"Given adequate penetration, a larger diameter bullet will have an edge in wounding effectiveness. It will damage a blood vessel the smaller projectile barely misses. The larger permanent cavity may lead to faster blood loss. Although such an edge clearly exists, its significance cannot be quantified".