Originally Posted by dkf
If you are concerned about over penetration you could buy some of those watered down Hornady Critical Defense rounds that are sold exclusively at Cabelas. I am not a fan of the Critical Defense and it is expensive but for what you want to do it would work ok for.
Well then you might as well carry a smaller/lighter 40.
"Given adequate penetration, a larger diameter bullet will have an edge in wounding effectiveness. It will damage a blood vessel the smaller projectile barely misses. The larger permanent cavity may lead to faster blood loss. Although such an edge clearly exists, its significance cannot be quantified".