I am not a fan of either round, but the 06 can handle heavier bullets w/ enough vel to take anything that walks the planet.
With 220gr solids, it has taken all the DG in Africa as well as the largest bears. I prefer a 280 & 338-06, but I am just a bit on the odd side.
"Given adequate penetration, a larger diameter bullet will have an edge in wounding effectiveness. It will damage a blood vessel the smaller projectile barely misses. The larger permanent cavity may lead to faster blood loss. Although such an edge clearly exists, its significance cannot be quantified".
Last edited by fredj338; 11-12-2012 at 18:57..