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All vaccines show a reaction at the site. That's the nature of a vaccine. But when anaphylaxis occurs (rare) usually skin lesions appear more severe. Theses massive rxns are usually systemic. That being said the risk of a huge life threatening rxn is less than the risk of contracting a lethal childhood disease. Another reason they give them all at once is kids tend to be exposed to all those bugs in the wild at the same time. Why bother vaccinating for rubella when he is going to get one of the other three diseases covered in the shot.
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