The only real diff will be your OAL. If you are using starting data, then it isn't going to matter much. Just anothe reason to have multiple data ref points. A single source will never cut it.
"Given adequate penetration, a larger diameter bullet will have an edge in wounding effectiveness. It will damage a blood vessel the smaller projectile barely misses. The larger permanent cavity may lead to faster blood loss. Although such an edge clearly exists, its significance cannot be quantified".