Originally Posted by gunreviewonmyspace
As a note, do not take head shots with .22lr pistols as the skull is often not penetrated due to the slower velocity of a short barrel. Stick with pelvis and torso hits.
Again I say, tell that to James Brady and Robert Kennedy
At close range, from a handgun, a .22 will penetrate a skull. Its easier to shrug off a .22 round in your pelvis then it is to shrug off a .22 in you head.